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marco.hat-gar-keine-homepage.de
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☆ marco.hat-gar-keine-homepage.de. 18195 IN A 85.25.130.82
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Domain: hat-gar-keine-homepage.de
Nserver: nsa4.schlundtech.de
Nserver: nsb4.schlundtech.de
Nserver: nsc4.schlundtech.de
Nserver: nsd4.schlundtech.de
Status: connect
Changed: 2010-03-27T03:06:35+01:00
Brief facts about marco:
Macrophage receptor with collagenous structure is a protein that in humans is encoded by the MARCO gene. MARCO is a class A scavenger receptor that is found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors found most commonly on immune cells. Their defining feature is that they bind to polyanions and modified forms of a type of cholesterol called low-density lipoprotein. MARCO is able to bind and phagocytose these ligands and pathogen-associated molecular patterns, leading to the clearance of pathogens and cell signaling events that lead to inflammation. As part of the innate immune system, MARCO clears, or scavenges, pathogens, which leads to inflammatory responses. The scavenger receptor cysteine-rich domain at the end of the extracellular side of MARCO binds ligands to activate the subsequent immune responses.
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